Computational studies on glycosaminoglycan recognition of sialyl transferases.

Sankaranarayanan, Nehru Viji; Sistla, Srinivas; Nagarajan, Balaji; Chittum, John E; Lau, Joseph T Y; Desai, Umesh R

Sankaranarayanan, Nehru Viji; Sistla, Srinivas; Nagarajan, Balaji; Chittum, John E; Lau, Joseph T Y; Desai, Umesh R.

Afiliação

Sankaranarayanan NV; Department of Medicinal Chemistry, Virginia Commonwealth University, Virginia 23298, Richmond, USA.
Sistla S; Drug Discovery and Development, Virginia Commonwealth University, Institute for Structural Biology, Virginia 23219, Richmond, USA.
Nagarajan B; Department of Medicinal Chemistry, Virginia Commonwealth University, Virginia 23298, Richmond, USA.
Chittum JE; Drug Discovery and Development, Virginia Commonwealth University, Institute for Structural Biology, Virginia 23219, Richmond, USA.
Lau JTY; Department of Medicinal Chemistry, Virginia Commonwealth University, Virginia 23298, Richmond, USA.
Desai UR; Drug Discovery and Development, Virginia Commonwealth University, Institute for Structural Biology, Virginia 23219, Richmond, USA.

Glycobiology ; 33(7): 579-590, 2023 08 14.

Article em En | MEDLINE | ID: mdl-37171590

Assuntos

Glicosaminoglicanos; Transferases; Humanos; Glicosaminoglicanos/química; Transferases/metabolismo; Heparitina Sulfato/metabolismo; Sítios de Ligação; Simulação de Dinâmica Molecular

Palavras-chave

competitive binding; computational modeling; glycosaminoglycans; heparan sulfate; sialyl transferases

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transferases / Glicosaminoglicanos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transferases / Glicosaminoglicanos Idioma: En Ano de publicação: 2023 Tipo de documento: Article