Your browser doesn't support javascript.
loading
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models.
Costa-Machado, Luis Filipe; Garcia-Dominguez, Esther; McIntyre, Rebecca L; Lopez-Aceituno, Jose Luis; Ballesteros-Gonzalez, Álvaro; Tapia-Gonzalez, Andrea; Fabregat-Safont, David; Eisenberg, Tobias; Gomez, Jesús; Plaza, Adrian; Sierra-Ramirez, Aranzazu; Perez, Manuel; Villanueva-Bermejo, David; Fornari, Tiziana; Loza, María Isabel; Herradon, Gonzalo; Hofer, Sebastian J; Magnes, Christoph; Madeo, Frank; Duerr, Janet S; Pozo, Oscar J; Galindo, Maximo-Ibo; Del Pino, Isabel; Houtkooper, Riekelt H; Megias, Diego; Viña, Jose; Gomez-Cabrera, Mari Carmen; Fernandez-Marcos, Pablo J.
Afiliação
  • Costa-Machado LF; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM + CSIC, E28049, Madrid, Spain.
  • Garcia-Dominguez E; Kaertor Foundation, EMPRENDIA Building, Floor 2, Office 4, Campus Vida, E-15706, Santiago de Compostela, Spain, E-15706, Santiago de Compostela, Spain.
  • McIntyre RL; BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
  • Lopez-Aceituno JL; Freshage Research Group, Department of Physiology, Faculty of Medicine, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, University of Valencia, Valencia, Spain.
  • Ballesteros-Gonzalez Á; Laboratory Genetic Metabolic Diseases, Amsterdam Gastroenterology, Endocrinology, Metabolism, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  • Tapia-Gonzalez A; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM + CSIC, E28049, Madrid, Spain.
  • Fabregat-Safont D; Developmental Biology and Disease Models Group, Centro de Investigación Príncipe Felipe, 46012, Valencia, Spain.
  • Eisenberg T; Neural Plasticity Group, Centro de Investigación Príncipe Felipe, 46012, Valencia, Spain.
  • Gomez J; Applied Metabolomics Research Group, Hospital del Mar Medical Research Institute - (IMIM), Barcelona, Spain.
  • Plaza A; Environmental and Public Health Analytical Chemistry, Research Institute for Pesticides and Water, University Jaume I, 12006, Castelló de la Plana, Castellón, Spain.
  • Sierra-Ramirez A; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Humboldtstraße 50, 8010, Graz, Austria.
  • Perez M; BioTechMed Graz, 8010, Graz, Austria.
  • Villanueva-Bermejo D; Field of Excellence BioHealth - University of Graz, Graz, Austria.
  • Fornari T; Confocal Microscopy Unit, Biotechnology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029, Madrid, Spain.
  • Loza MI; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM + CSIC, E28049, Madrid, Spain.
  • Herradon G; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM + CSIC, E28049, Madrid, Spain.
  • Hofer SJ; Confocal Microscopy Unit, Biotechnology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029, Madrid, Spain.
  • Magnes C; Department of Production and Characterization of Novel Foods, Institute of Food Science Research (CIAL UAM-CSIC), C/ Nicolás Cabrera, 9, P.O. Box. 28049, Madrid, Spain.
  • Madeo F; Department of Production and Characterization of Novel Foods, Institute of Food Science Research (CIAL UAM-CSIC), C/ Nicolás Cabrera, 9, P.O. Box. 28049, Madrid, Spain.
  • Duerr JS; Kaertor Foundation, EMPRENDIA Building, Floor 2, Office 4, Campus Vida, E-15706, Santiago de Compostela, Spain, E-15706, Santiago de Compostela, Spain.
  • Pozo OJ; BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
  • Galindo MI; Lab. Pharmacology, Faculty of Pharmacy, Universidad CEU San Pablo, Urb. Montepríncipe, 28668, Boadilla del Monte, Madrid, Spain.
  • Del Pino I; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Humboldtstraße 50, 8010, Graz, Austria.
  • Houtkooper RH; BioTechMed Graz, 8010, Graz, Austria.
  • Megias D; Field of Excellence BioHealth - University of Graz, Graz, Austria.
  • Viña J; HEALTH-Institute for Biomedicine and Health Sciences, Joanneum Research Forschungsgesellschaft mbH, 8010, Graz, Austria.
  • Gomez-Cabrera MC; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Humboldtstraße 50, 8010, Graz, Austria.
  • Fernandez-Marcos PJ; BioTechMed Graz, 8010, Graz, Austria.
Nat Commun ; 14(1): 2779, 2023 05 15.
Article em En | MEDLINE | ID: mdl-37188705
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Receptores de GABA-A / Mitofagia / Harmina / Mitocôndrias / Monoaminoxidase / Antidepressivos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Receptores de GABA-A / Mitofagia / Harmina / Mitocôndrias / Monoaminoxidase / Antidepressivos Idioma: En Ano de publicação: 2023 Tipo de documento: Article