Modified Rotational Thromboelastometry Protocol Using Tissue Plasminogen Activator for Detection of Hypofibrinolysis and Hyperfibrinolysis.
Methods Mol Biol
; 2663: 763-773, 2023.
Article
em En
| MEDLINE
| ID: mdl-37204751
ABSTRACT
Viscoelastic testing includes thromboelastography (TEG®) and thromboelastometry (ROTEM®) and is widely used in bleeding patients to detect hypocoagulability and guide transfusion therapy. However, the ability of standard viscoelastic tests to assess fibrinolytic capacity is limited. We here describe a modified ROTEM® protocol with addition of tissue plasminogen activator that can be used to identify hypofibrinolysis or hyperfibrinolysis.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Tromboelastografia
/
Transtornos da Coagulação Sanguínea
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article