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Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays.
Li, Xilin; Le, Yuan; Seo, Ji-Eun; Guo, Xiaoqing; Li, Yuxi; Chen, Si; Mittelstaedt, Roberta A; Moore, Nyosha; Guerrero, Sharon; Sims, Audrey; King, Sruthi T; Atrakchi, Aisar H; McGovern, Timothy J; Davis-Bruno, Karen L; Keire, David A; Elespuru, Rosalie K; Heflich, Robert H; Mei, Nan.
Afiliação
  • Li X; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA. Electronic address: xilin.li@fda.hhs.gov.
  • Le Y; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Seo JE; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Guo X; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Li Y; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Chen S; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Mittelstaedt RA; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Moore N; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Guerrero S; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Sims A; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • King ST; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, 20993, USA.
  • Atrakchi AH; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, 20993, USA.
  • McGovern TJ; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, 20993, USA.
  • Davis-Bruno KL; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, 20993, USA.
  • Keire DA; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, 20993, USA.
  • Elespuru RK; Discovery Life Sciences, Columbia, MD, 21045, USA.
  • Heflich RH; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Mei N; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA. Electronic address: nan.mei@fda.hhs.gov.
Regul Toxicol Pharmacol ; 141: 105410, 2023 Jun.
Article em En | MEDLINE | ID: mdl-37210026
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propranolol / Mutagênicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propranolol / Mutagênicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article