RIPK2 promotes the progression of colon cancer by regulating BIRC3-mediated ubiquitination of IKBKG.

Zhang, Zhiyong; Pan, Yan; Zhao, Yan; Ren, Mudan; Li, Yarui; Lu, Guifang; He, Shuixiang

Zhang, Zhiyong; Pan, Yan; Zhao, Yan; Ren, Mudan; Li, Yarui; Lu, Guifang; He, Shuixiang.

Afiliação

Zhang Z; Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Pan Y; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases, And Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China.
Zhao Y; Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Ren M; Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Li Y; Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
Lu G; Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
He S; Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China. Electronic address: shuixiang_he@126.com.

Exp Cell Res ; 429(1): 113644, 2023 08 01.

Article em En | MEDLINE | ID: mdl-37211186

Assuntos

Neoplasias do Colo; NF-kappa B; Humanos; Animais; Camundongos; NF-kappa B/metabolismo; Ubiquitinação; Transdução de Sinais; Ubiquitina-Proteína Ligases/genética; Ubiquitina-Proteína Ligases/metabolismo; Neoplasias do Colo/genética; Proteína 3 com Repetições IAP de Baculovírus/genética; Proteína 3 com Repetições IAP de Baculovírus/metabolismo; Proteína Serina-Treonina Quinase 2 de Interação com Receptor/genética; Proteína Serina-Treonina Quinase 2 de Interação com Receptor/metabolismo; Quinase I-kappa B/genética; Quinase I-kappa B/metabolismo

Palavras-chave

Colon cancer; IKBKG; NF-κB signaling pathway; RIPK2-BIRC3 interaction; Ubiquitination

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Neoplasias do Colo Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Neoplasias do Colo Idioma: En Ano de publicação: 2023 Tipo de documento: Article