Modulation of WNT, Activin/Nodal, and MAPK Signaling Pathways Increases Arterial Hemogenic Endothelium and Hematopoietic Stem/Progenitor Cell Formation During Human iPSC Differentiation.

Li, Yongqin; Ding, Jianyi; Araki, Daisuke; Zou, Jizhong; Larochelle, Andre

Li, Yongqin; Ding, Jianyi; Araki, Daisuke; Zou, Jizhong; Larochelle, Andre.

Afiliação

Li Y; Cellular and Molecular Therapeutics Branch, National Heart, Lung and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, USA.
Ding J; Cellular and Molecular Therapeutics Branch, National Heart, Lung and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, USA.
Araki D; Cellular and Molecular Therapeutics Branch, National Heart, Lung and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, USA.
Zou J; iPSC Core Facility, NHLBI, NIH, Bethesda, MD, USA.
Larochelle A; Cellular and Molecular Therapeutics Branch, National Heart, Lung and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, USA.

Stem Cells ; 41(7): 685-697, 2023 Jul 14.

Article em En | MEDLINE | ID: mdl-37220178

Assuntos

Hemangioblastos; Células-Tronco Pluripotentes Induzidas; Humanos; Células-Tronco Pluripotentes Induzidas/metabolismo; Ativinas/metabolismo; Diferenciação Celular; Transdução de Sinais

Palavras-chave

Activin/Nodal; WNT and MAPK signaling pathways; arterial hemogenic endothelium; hematopoietic stem/progenitor cells; induced pluripotent stem cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemangioblastos / Células-Tronco Pluripotentes Induzidas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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