Siderophore conjugation with cleavable linkers boosts the potency of RNA polymerase inhibitors against multidrug-resistant <i>E. coli</i>.

Siderophore conjugation with cleavable linkers boosts the potency of RNA polymerase inhibitors against multidrug-resistant E. coli.

Peukert, Carsten; Vetter, Anna C; Fuchs, Hazel L S; Harmrolfs, Kirsten; Karge, Bianka; Stadler, Marc; Brönstrup, Mark.

Afiliação

Peukert C; Department of Chemical Biology, Helmholtz Centre for Infection Research Inhoffenstraße 7 38124 Braunschweig Germany Mark.Broenstrup@helmholtz-hzi.de.
Vetter AC; Department of Chemical Biology, Helmholtz Centre for Infection Research Inhoffenstraße 7 38124 Braunschweig Germany Mark.Broenstrup@helmholtz-hzi.de.
Fuchs HLS; Department of Chemical Biology, Helmholtz Centre for Infection Research Inhoffenstraße 7 38124 Braunschweig Germany Mark.Broenstrup@helmholtz-hzi.de.
Harmrolfs K; Department of Chemical Biology, Helmholtz Centre for Infection Research Inhoffenstraße 7 38124 Braunschweig Germany Mark.Broenstrup@helmholtz-hzi.de.
Karge B; Department of Chemical Biology, Helmholtz Centre for Infection Research Inhoffenstraße 7 38124 Braunschweig Germany Mark.Broenstrup@helmholtz-hzi.de.
Stadler M; Department of Microbial Drugs, Helmholtz Centre for Infection Research Inhoffenstraße 7 38124 Braunschweig Germany.
Brönstrup M; German Center for Infection Research (DZIF) Site Hannover-Braunschweig, Inhoffenstraße 7 38124 Braunschweig Germany.

Chem Sci ; 14(20): 5490-5502, 2023 May 24.

Article em En | MEDLINE | ID: mdl-37234900

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article