A Case Report of Early-Onset Alzheimer's Disease Using 18F-FDG PET and 18F-FBB PET.
Diagnostics (Basel)
; 13(10)2023 May 09.
Article
em En
| MEDLINE
| ID: mdl-37238154
ABSTRACT
We describe a 40-year-old female patient who presented with sleep disturbance, intermittent headache, and gradual subjective cognitive decline. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed mild FDG hypometabolism in bilateral parietal and temporal lobes. However, 18F-florbetaben (FBB) amyloid PET revealed diffuse amyloid retention in the lateral temporal cortex, frontal cortex, posterior cingulate cortex/precuneus, parietal cortex, and cerebellum. This finding supports the clinical significance of amyloid imaging in diagnostic work-up of early-onset Alzheimer's disease (EOAD).
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MEDLINE
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En
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2023
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Article