Prenatal Fumonisin Exposure Impairs Bone Development via Disturbances in the OC/Leptin and RANKL/RANK/OPG Systems in Weaned Rat Offspring.

Tomaszewska, Ewa; Rudyk, Halyna; Muszynski, Siemowit; Hulas-Stasiak, Monika; Leszczynski, Norbert; Mielnik-Blaszczak, Maria; Donaldson, Janine; Dobrowolski, Piotr

Tomaszewska, Ewa; Rudyk, Halyna; Muszynski, Siemowit; Hulas-Stasiak, Monika; Leszczynski, Norbert; Mielnik-Blaszczak, Maria; Donaldson, Janine; Dobrowolski, Piotr.

Afiliação

Tomaszewska E; Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Rudyk H; Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Muszynski S; Laboratory of Feed Additives and Premixtures Control, State Research Control Institute of Veterinary Drugs and Feed Additives, 79000 Lviv, Ukraine.
Hulas-Stasiak M; Department of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Leszczynski N; Department of Functional Anatomy and Cytobiology, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, 20-033 Lublin, Poland.
Mielnik-Blaszczak M; Department of Agricultural, Forest and Transport Machinery, Faculty of Production Engineering, University of Life Sciences in Lublin, 20-612 Lublin, Poland.
Donaldson J; Chair and Department of Developmental Dentistry, Medical University of Lublin, 20-081 Lublin, Poland.
Dobrowolski P; School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Parktown, Johannesburg 2193, South Africa.

Int J Mol Sci ; 24(10)2023 May 14.

Article em En | MEDLINE | ID: mdl-37240089

Assuntos

Fumonisinas; Osteoprotegerina; Ratos; Masculino; Feminino; Animais; Osteoprotegerina/genética; Osteoprotegerina/metabolismo; Receptor Ativador de Fator Nuclear kappa-B/metabolismo; Fumonisinas/toxicidade; Leptina; Ligantes; NF-kappa B/metabolismo; Desenvolvimento Ósseo; Ligante RANK/genética; Ligante RANK/metabolismo

Palavras-chave

MMP-8; OPG; RANKL; TIMP-2; VEGF; bone; expression; fumonisin; weaned rats

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fumonisinas / Osteoprotegerina Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fumonisinas / Osteoprotegerina Idioma: En Ano de publicação: 2023 Tipo de documento: Article