Chemical Analysis and Molecular Modelling of Cyclodextrin-Formulated Propofol and Its Sodium Salt to Improve Drug Solubility, Stability and Pharmacokinetics (Cytogenotoxicity).

Wilhelms, Benedikt; Broscheit, Jens; Shityakov, Sergey

Wilhelms, Benedikt; Broscheit, Jens; Shityakov, Sergey.

Afiliação

Wilhelms B; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, Würzburg University Hospital, 97080 Würzburg, Germany.
Broscheit J; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, Würzburg University Hospital, 97080 Würzburg, Germany.
Shityakov S; Infochemistry Scientific Center, Laboratory of Chemoinformatics, ITMO University, Saint Petersburg 191002, Russia.

Pharmaceuticals (Basel) ; 16(5)2023 Apr 28.

Article em En | MEDLINE | ID: mdl-37242449