Cholestasis-Associated Pulmonary Inflammation, Oxidative Stress, and Tissue Fibrosis: The Protective Role of the Biogenic Amine Agmatine.

Ommati, Mohammad Mehdi; Niknahad, Hossein; Najibi, Asma; Arjmand, Abdollah; Alidaee, Sepideh; Mazloomi, Sahra; Ahmadi, Parinaz; Ghiasvand, Alireza; Javadi, Maral; Yazdani, Jamal; Sabouri, Samira; Rezaei, Heresh; Azarpira, Negar; Heidari, Reza

Ommati, Mohammad Mehdi; Niknahad, Hossein; Najibi, Asma; Arjmand, Abdollah; Alidaee, Sepideh; Mazloomi, Sahra; Ahmadi, Parinaz; Ghiasvand, Alireza; Javadi, Maral; Yazdani, Jamal; Sabouri, Samira; Rezaei, Heresh; Azarpira, Negar; Heidari, Reza.

Afiliação

Ommati MM; College of Veterinary Medicine, Shanxi Agricultural University, Taigu, China, mehdi_ommati@outlook.com.
Niknahad H; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, mehdi_ommati@outlook.com.
Najibi A; Henan Key Laboratory of Environmental and Animal Product Safety, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China, mehdi_ommati@outlook.com.
Arjmand A; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Alidaee S; Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Mazloomi S; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ahmadi P; Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Ghiasvand A; Department of Toxicology and Pharmacology, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Javadi M; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Yazdani J; Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Sabouri S; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Rezaei H; Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Azarpira N; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Heidari R; Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

Pharmacology ; 108(4): 379-393, 2023.

Article em En | MEDLINE | ID: mdl-37253339

Assuntos

Agmatina; Colestase; Lesão Pulmonar; Pneumonia; Masculino; Camundongos; Humanos; Animais; Agmatina/farmacologia; Agmatina/uso terapêutico; Agmatina/metabolismo; Camundongos Endogâmicos C57BL; Colestase/complicações; Colestase/tratamento farmacológico; Colestase/metabolismo; Fígado; Estresse Oxidativo; Fibrose; Pneumonia/tratamento farmacológico; Pneumonia/prevenção & controle; Pneumonia/complicações; Biomarcadores/metabolismo; Citocinas/metabolismo; Aminas Biogênicas/metabolismo; Aminas Biogênicas/farmacologia

Palavras-chave

Agmatine; Bile acid; Cytokine; Inflammation; Liver-lung axis; Pharmacotherapy; Pulmonary damage

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia / Colestase / Agmatina / Lesão Pulmonar Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia / Colestase / Agmatina / Lesão Pulmonar Idioma: En Ano de publicação: 2023 Tipo de documento: Article