Acquisition of a large virulence plasmid (pINV) promoted temperature-dependent virulence and global dispersal of O96:H19 enteroinvasive <i>Escherichia coli</i>.

Miles, Sydney L; Torraca, Vincenzo; Dyson, Zoe A; López-Jiménez, Ana Teresa; Foster-Nyarko, Ebenezer; Lobato-Márquez, Damián; Jenkins, Claire; Holt, Kathryn E; Mostowy, Serge

Acquisition of a large virulence plasmid (pINV) promoted temperature-dependent virulence and global dispersal of O96:H19 enteroinvasive Escherichia coli.

Miles, Sydney L; Torraca, Vincenzo; Dyson, Zoe A; López-Jiménez, Ana Teresa; Foster-Nyarko, Ebenezer; Lobato-Márquez, Damián; Jenkins, Claire; Holt, Kathryn E; Mostowy, Serge.

Afiliação

Miles SL; Department of Infection Biology, London School of Hygiene and Tropical Medicine , London, United Kingdom.
Torraca V; Department of Infection Biology, London School of Hygiene and Tropical Medicine , London, United Kingdom.
Dyson ZA; Department of Infection Biology, London School of Hygiene and Tropical Medicine , London, United Kingdom.
López-Jiménez AT; Department of Infectious Diseases, Central Clinical School, Monash University , Melbourne, Victoria, Australia.
Foster-Nyarko E; Wellcome Sanger Institute, Wellcome Genome Campus , Hinxton, United Kingdom.
Lobato-Márquez D; Department of Infection Biology, London School of Hygiene and Tropical Medicine , London, United Kingdom.
Jenkins C; Department of Infection Biology, London School of Hygiene and Tropical Medicine , London, United Kingdom.
Holt KE; Department of Infection Biology, London School of Hygiene and Tropical Medicine , London, United Kingdom.
Mostowy S; Gastrointestinal Pathogens and Food Safety (One Health), UK Health Security Agency , London, United Kingdom.

mBio ; 14(4): e0088223, 2023 08 31.

Article em En | MEDLINE | ID: mdl-37255304

Assuntos

Disenteria Bacilar; Infecções por Escherichia coli; Shigella; Animais; Humanos; Escherichia coli; Virulência/genética; Peixe-Zebra; Sistemas de Secreção Tipo III/genética; Teorema de Bayes; Temperatura; Plasmídeos/genética; Shigella/genética

Palavras-chave

EIEC; Enterobacteriaceae; Shigella; evolution; host-pathogen interactions; virulence determinants; zebrafish

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Shigella / Disenteria Bacilar / Infecções por Escherichia coli Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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