Xanthatin induce DDP-resistance lung cancer cells apoptosis through regulation of GLUT1 mediated ROS accumulation.

Liu, Yunxiao; Zhang, Xinge; Cheng, Fenting; Cao, Wei; Geng, Yadi; Chen, Zhaolin; Wei, Wei; Zhang, Lei

Liu, Yunxiao; Zhang, Xinge; Cheng, Fenting; Cao, Wei; Geng, Yadi; Chen, Zhaolin; Wei, Wei; Zhang, Lei.

Afiliação

Liu Y; Key Laboratory of Anti-Inflammatory and Immune Medicine, Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China.
Zhang X; Key Laboratory of Anti-Inflammatory and Immune Medicine, Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China.
Cheng F; Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Cao W; Key Laboratory of Anti-Inflammatory and Immune Medicine, Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China.
Geng Y; Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Chen Z; Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Wei W; Key Laboratory of Anti-Inflammatory and Immune Medicine, Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China.
Zhang L; Key Laboratory of Anti-Inflammatory and Immune Medicine, Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China.

Drug Dev Res ; 84(6): 1266-1278, 2023 09.

Article em En | MEDLINE | ID: mdl-37260173

Assuntos

Antineoplásicos; Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Humanos; Espécies Reativas de Oxigênio/metabolismo; Transportador de Glucose Tipo 1; Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico; Resistencia a Medicamentos Antineoplásicos; Linhagem Celular Tumoral; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/metabolismo; Cisplatino/farmacologia; Apoptose; Proliferação de Células; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico

Palavras-chave

ROS; Xanthatin; csplatin resistance lung cancer; glucose transporter 1; pentose phosphate pathway

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google