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Suicide risk classification with machine learning techniques in a large Brazilian community sample.
Roza, Thiago Henrique; Seibel, Gabriel de Souza; Recamonde-Mendoza, Mariana; Lotufo, Paulo A; Benseñor, Isabela M; Passos, Ives Cavalcante; Brunoni, Andre Russowsky.
Afiliação
  • Roza TH; Department of Psychiatry, Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil; Laboratory of Molecular Psychiatry, Centro de Pesquisa Experimental (CPE) and Centro de Pesquisa Clínica (CPC), Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil; Graduate Program in Psychiatry
  • Seibel GS; Institute of Informatics, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Electronic address: gabrielseibel1@gmail.com.
  • Recamonde-Mendoza M; Institute of Informatics, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil; Bioinformatics Core, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. Electronic address: mrmendoza@inf.ufrgs.br.
  • Lotufo PA; Department of Internal Medicine, Faculty of Medicine, Universidade de São Paulo (USP), São Paulo, SP, Brazil. Electronic address: palotufo@usp.br.
  • Benseñor IM; Department of Internal Medicine, Faculty of Medicine, Universidade de São Paulo (USP), São Paulo, SP, Brazil. Electronic address: isabensenor@gmail.com.
  • Passos IC; Laboratory of Molecular Psychiatry, Centro de Pesquisa Experimental (CPE) and Centro de Pesquisa Clínica (CPC), Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil; Graduate Program in Psychiatry and Behavioral Sciences, Department of Psychiatry, Faculty of Medicine, Universidade F
  • Brunoni AR; Department of Psychiatry and Laboratory of Neurosciences (LIM-27), Institute of Psychiatry, Universidade de São Paulo (USP), São Paulo, SP, Brazil. Electronic address: brunowsky@gmail.com.
Psychiatry Res ; 325: 115258, 2023 07.
Article em En | MEDLINE | ID: mdl-37263086
ABSTRACT
Even though suicide is a relatively preventable poor outcome, its prediction remains an elusive task. The main goal of this study was to develop machine learning classifiers to identify increased suicide risk in Brazilians with common mental disorders. With the use of clinical and sociodemographic baseline data (n = 4039 adult participants) from a large Brazilian community sample, we developed several models (Elastic Net, Random Forests, Naïve Bayes, and ensemble) for the classification of increased suicide risk among individuals with common mental disorders. 1120 participants (27.7%) presented increased suicide risk. The Random Forests model achieved the best AUC ROC (0.814), followed by Naive Bayes (0.798) and Elastic Net (0.773). Sensitivity varied from 0.922 (Naive Bayes) to 0.630 (Random Forests), while specificity varied from 0.792 (Random Forests) to 0.473 (Naive Bayes). The ensemble model presented an AUC ROC of 0.811, sensitivity of 0.899, and specificity of 0.510. Features representing depression symptoms were the most relevant for the classification of increased suicide risk. Some of our models presented good performance metrics in the classification of increased suicide risk in the investigated sample, which can provide the means to early preventive interventions.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Suicídio / Transtornos Mentais Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Suicídio / Transtornos Mentais Idioma: En Ano de publicação: 2023 Tipo de documento: Article