Assessing the quality consistency of red yeast medicinal material by five-wavelength fusion fingerprint and ultraviolet quantum fingerprint corresponding with antioxidant activity analysis.
J Pharm Biomed Anal
; 233: 115493, 2023 Sep 05.
Article
em En
| MEDLINE
| ID: mdl-37267873
ABSTRACT
In this study, a five-wavelength fusion fingerprint (FWFFT) combined with all-ultraviolet(UV) and antioxidant methods was used to explore the quality consistency of red yeast (RYT) samples. 1,1-Diphenyl-2-picrylhydrazyl Free Radical (DPPH) was used for antioxidant experiments, combined with high performance liquid chromatography (HPLC), and grey correlation analysis (GCA) was performed with chromatographic peak area. The results showed that multi-wavelength fusion technology compensates for the shortcomings of single-wavelength technology, and the combination with UV avoids of the one-sidedness of single technology. Simultaneously, the fingerprint peak of the sample and the antioxidant activity had a high correlation, and the antioxidant activity had a corresponding relationship with the content of the two controls. This study provides a comprehensive and reliable method for the quality consistency evaluation of traditional Chinese medicines (TCM).
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Base de dados:
MEDLINE
Assunto principal:
Medicamentos de Ervas Chinesas
/
Antioxidantes
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article