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Treatment of a case of primary alveolar soft part sarcoma of the lung: Case report and literature review.
Li, Feiyang; Lu, Haowei; Zhao, Dong; Shen, Zhiyuan.
Afiliação
  • Li F; Ward 2, Department of Medical Oncology, Lixin County People's Hospital, Bozhou, Anhui Province, China.
  • Lu H; Ward 2, Department of Medical Oncology, Lixin County People's Hospital, Bozhou, Anhui Province, China.
  • Zhao D; Ward 2, Department of Medical Oncology, Lixin County People's Hospital, Bozhou, Anhui Province, China.
  • Shen Z; Ward 2, Department of Medical Oncology, Lixin County People's Hospital, Bozhou, Anhui Province, China.
J Int Med Res ; 51(6): 3000605231174973, 2023 Jun.
Article em En | MEDLINE | ID: mdl-37282499
Alveolar soft part sarcoma (ASPS) is an extremely rare type of soft tissue sarcoma. The primary sites of ASPS are mostly located in the extremities and trunk. Primary pulmonary ASPS is extremely rare. A search of the PubMed® database identified only five cases of primary pulmonary ASPS. This current case report describes the sixth case of ASPS in a 15-year-old male that presented with recurrent headaches. Head computed tomography showed space-occupying lesions in the left parietal lobe. Positron emission tomography-computed tomography confirmed the space-occupying lesions in the left parietal lobe and showed multiple nodules and masses in the two lungs and pleura, which were considered to be low-grade malignant mesenchymal tumours. The case report presents the clinical characteristics, diagnosis and treatment process. Programmed cell death protein 1 monoclonal antibody (sintilimab) combined with a tyrosine kinase inhibitor (anlotinib hydrochloride) achieved a good therapeutic effect, indicating that this combination therapy is worth exploring further. Large-scale prospective studies are needed to explore and develop standardized treatments for ASPS.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias de Tecidos Moles / Sarcoma Alveolar de Partes Moles Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias de Tecidos Moles / Sarcoma Alveolar de Partes Moles Idioma: En Ano de publicação: 2023 Tipo de documento: Article