Photothermal-Switched Single-Atom Nanozyme Specificity for Pretreatment and Sensing.
Small
; 19(40): e2302929, 2023 10.
Article
em En
| MEDLINE
| ID: mdl-37282757
ABSTRACT
Various applications lead to the requirement of nanozymes with either specific activity or multiple enzyme-like activities. To this end, intelligent nanozymes with freely switching specificity abilities hold great promise to adapt to complicated and changeable practical conditions. Herein, a nitrogen-doped carbon-supported copper single-atom nanozyme (named Cu SA/NC) with switchable specificity is reported. Atomically dispersed active sites endow Cu SA/NC with specific peroxidase-like activity at room temperature. Furthermore, the intrinsic photothermal conversion ability of Cu SA/NC enables the specificity switch by additional laser irradiation, where photothermal-induced temperature elevation triggers the expression of oxidase-like and catalase-like activity of Cu SA/NC. For further applications in practice, a pretreatment-and-sensing integration kit (PSIK) is constructed, where Cu SA/NC can successively achieve sample pretreatment and sensitive detection by switching from multi-activity mode to specific-activity mode. This study sets the foundation for nanozymes with switchable specificity and broadens the application scope in point-of-care testing.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Carbono
/
Cobre
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article