The AMPK-dependent inhibition of autophagy plays a crucial role in protecting photoreceptor from photooxidative injury.

Li, Yu-Lin; Zhang, Tian-Zi; Han, Li-Kun; He, Chang; Pan, Yi-Ran; Fan, Bin; Li, Guang-Yu

Li, Yu-Lin; Zhang, Tian-Zi; Han, Li-Kun; He, Chang; Pan, Yi-Ran; Fan, Bin; Li, Guang-Yu.

Afiliação

Li YL; Department of Ophthalmology, The Second Norman Bethune Hospital of JiLin University, ChangChun, China.
Zhang TZ; Affiliated Hospital of Inner Mongolia University for the Nationalities, Inner Mongolia, China.
Han LK; Affiliated Hospital of Inner Mongolia University for the Nationalities, Inner Mongolia, China.
He C; Affiliated Hospital of Inner Mongolia University for the Nationalities, Inner Mongolia, China.
Pan YR; Department of Ophthalmology, The Second Norman Bethune Hospital of JiLin University, ChangChun, China.
Fan B; Department of Ophthalmology, The Second Norman Bethune Hospital of JiLin University, ChangChun, China. Electronic address: fanb@jlu.edu.cn.
Li GY; Department of Ophthalmology, The Second Norman Bethune Hospital of JiLin University, ChangChun, China. Electronic address: l_gy@jlu.edu.cn.

J Photochem Photobiol B ; 245: 112735, 2023 Aug.

Article em En | MEDLINE | ID: mdl-37302156

Assuntos

Proteínas Quinases Ativadas por AMP; Fármacos Neuroprotetores; Camundongos; Animais; Proteínas Quinases Ativadas por AMP/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Transdução de Sinais; Células Fotorreceptoras/metabolismo; Fármacos Neuroprotetores/farmacologia; Sirolimo/farmacologia; Autofagia; Mamíferos/metabolismo

Palavras-chave

AMPK; Autophagy; Photooxidation; Photoreceptor; Retinal light injury; Retinal neuroprotection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Proteínas Quinases Ativadas por AMP Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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