Catalyst-Free Synthesis of Polycyclic Spiroindolines by Cascade Reaction of 3-(2-Isocyanoethyl)indoles with 1-Sulfonyl-1,2,3-triazoles.
J Org Chem
; 88(13): 9543-9553, 2023 Jul 07.
Article
em En
| MEDLINE
| ID: mdl-37307412
ABSTRACT
A catalyst-free cascade reaction of 3-(2-isocyanoethyl)indoles and 1-sulfonyl-1,2,3-triazoles was realized. This dearomative spirocyclization provided an efficient protocol to synthesize a series of polycyclic indolines bearing spiro-α-carboline in moderate to high yields in one step under thermal reaction conditions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Triazóis
/
Indóis
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article