Acute osimertinib exposure induces electrocardiac changes by synchronously inhibiting the currents of cardiac ion channels.

Li, Peiwen; Tian, Xiaohui; Wang, Gongxin; Jiang, Enshe; Li, Yanming; Hao, Guoliang.

Afiliação

Li P; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, China.
Tian X; Department of Pharmacy, Huaihe Hospital of Henan University, Kaifeng, China.
Wang G; Department of Research, Scope Research Institute of Electrophysiology, Kaifeng, China.
Jiang E; Institute of Nursing and Health, Henan University, Kaifeng, China.
Li Y; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, China.
Hao G; Department of Research, Scope Research Institute of Electrophysiology, Kaifeng, China.

Front Pharmacol ; 14: 1177003, 2023.

Article em En | MEDLINE | ID: mdl-37324483