Erdafitinib in the Treatment of Metastatic Urothelial Carcinoma.
Oncology (Williston Park)
; 37(6): 256-261, 2023 06 12.
Article
em En
| MEDLINE
| ID: mdl-37343207
ABSTRACT
A Hispanic man, aged 42 years, was diagnosed with stage IV metastatic urothelial bladder cancer (MUBC) with nonregional lymphadenopathies and lung, bone, and skin involvement. He received first-line treatment with gemcitabine and cisplatin for 6 cycles, achieving a partial response (PR). Next, he received immunotherapy maintenance with avelumab for 4 months until disease progression. A next-generation sequencing test of paraffin-embedded tumor tissue identified a fibroblast growth factor receptor 3 (FGFR3) S249C missense mutation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Bexiga Urinária
/
Carcinoma de Células de Transição
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article