Multi-Enzyme Cascade-Triggered Nitric Oxide Release Nanoplatform Combined with Chemo Starvation-like Therapy for Multidrug-Resistant Cancers.

Li, Ge; Lu, Xinyue; Zhang, Shixin; Zhang, Jingbo; Fu, Xiaoge; Zhang, Miaomiao; Teng, Lesheng; Sun, Fengying

Li, Ge; Lu, Xinyue; Zhang, Shixin; Zhang, Jingbo; Fu, Xiaoge; Zhang, Miaomiao; Teng, Lesheng; Sun, Fengying.

Afiliação

Li G; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Lu X; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Zhang S; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Zhang J; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Fu X; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Zhang M; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Teng L; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Sun F; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.

ACS Appl Mater Interfaces ; 15(26): 31285-31299, 2023 Jul 05.

Article em En | MEDLINE | ID: mdl-37344958

Assuntos

Nanopartículas; Neoplasias; Humanos; Óxido Nítrico; Resistência a Múltiplos Medicamentos; Peróxido de Hidrogênio; Espécies Reativas de Oxigênio; Resistencia a Medicamentos Antineoplásicos; Neoplasias/tratamento farmacológico; Arginina; Linhagem Celular Tumoral; Microambiente Tumoral

Palavras-chave

MOF; ZIF-8; chemodynamic therapy; ferroptosis; gas therapy; multidrug resistance

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas / Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas / Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article