Islets in the body are never flat: transitioning from two-dimensional (2D) monolayer culture to three-dimensional (3D) spheroid for better efficiency in the generation of functional hPSC-derived pancreatic ß cells in vitro.

Diane, Abdoulaye; Mohammed, Layla Ibrahim; Al-Siddiqi, Heba H

Diane, Abdoulaye; Mohammed, Layla Ibrahim; Al-Siddiqi, Heba H.

Afiliação

Diane A; Diabetes Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation (QF), Doha, Qatar. adiane@hbku.edu.qa.
Mohammed LI; Diabetes Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation (QF), Doha, Qatar.
Al-Siddiqi HH; Diabetes Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation (QF), Doha, Qatar.

Cell Commun Signal ; 21(1): 151, 2023 06 22.

Article em En | MEDLINE | ID: mdl-37349801

Assuntos

Células Secretoras de Insulina; Diferenciação Celular; Células-Tronco

Palavras-chave

Differentiation; Three-dimension (3D); Two-dimension (2D); hPSC; ß cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Secretoras de Insulina Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Secretoras de Insulina Idioma: En Ano de publicação: 2023 Tipo de documento: Article