Lower Circulating Cytotoxic T-Cell Frequency and Higher Intragraft Granzyme-B Expression Are Associated with Inflammatory Interstitial Fibrosis and Tubular Atrophy in Renal Allograft Recipients.

Yadav, Brijesh; Prasad, Narayan; Agrawal, Vinita; Agarwal, Vikas; Jain, Manoj

Yadav, Brijesh; Prasad, Narayan; Agrawal, Vinita; Agarwal, Vikas; Jain, Manoj.

Afiliação

Yadav B; Department of Nephrology and Renal Transplantation, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Prasad N; Department of Nephrology and Renal Transplantation, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Agrawal V; Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Agarwal V; Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Jain M; Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.

Medicina (Kaunas) ; 59(6)2023 Jun 20.

Article em En | MEDLINE | ID: mdl-37374379

Assuntos

Nefropatias; Transplante de Rim; Humanos; Transplante de Rim/efeitos adversos; Linfócitos T Citotóxicos; Granzimas/metabolismo; Linfócitos T CD8-Positivos; Leucócitos Mononucleares; Creatinina/metabolismo; Túbulos Renais/metabolismo; Túbulos Renais/patologia; Nefropatias/patologia; Fibrose; Aloenxertos; Proteinúria; Atrofia; RNA Mensageiro/genética; RNA Mensageiro/metabolismo

Palavras-chave

cytotoxic T lymphocyte; granzyme B; inflammatory interstitial fibrosis and tubular atrophy; stable graft function

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Rim / Nefropatias Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Rim / Nefropatias Idioma: En Ano de publicação: 2023 Tipo de documento: Article