Neurochemistry of the mammillary body.
Brain Struct Funct
; 228(6): 1379-1398, 2023 Jul.
Article
em En
| MEDLINE
| ID: mdl-37378855
ABSTRACT
The mammillary body (MB) is a component of the extended hippocampal system and many studies have shown that its functions are vital for mnemonic processes. Together with other subcortical structures, such as the anterior thalamic nuclei and tegmental nuclei of Gudden, the MB plays a crucial role in the processing of spatial and working memory, as well as navigation in rats. The aim of this paper is to review the distribution of various substances in the MB of the rat, with a description of their possible physiological roles. The following groups of substances are reviewed (1) classical neurotransmitters (glutamate and other excitatory transmitters, gamma-aminobutyric acid, acetylcholine, serotonin, and dopamine), (2) neuropeptides (enkephalins, substance P, cocaine- and amphetamine-regulated transcript, neurotensin, neuropeptide Y, somatostatin, orexins, and galanin), and (3) other substances (calcium-binding proteins and calcium sensor proteins). This detailed description of the chemical parcellation may facilitate a better understanding of the MB functions and its complex relations with other structures of the extended hippocampal system.
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Base de dados:
MEDLINE
Assunto principal:
Núcleos Anteriores do Tálamo
/
Neuroquímica
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article