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Optimization of Drug-Linker to Enable Long-term Storage of Antibody-Drug Conjugate for Subcutaneous Dosing.
Hobson, Adrian D; Xu, Jianwen; Marvin, Christopher C; McPherson, Michael J; Hollmann, Markus; Gattner, Michael; Dzeyk, Kristina; Fettis, Margaret M; Bischoff, Agnieszka K; Wang, Lu; Fitzgibbons, Julia; Wang, Lu; Salomon, Paulin; Hernandez, Axel; Jia, Ying; Sarvaiya, Hetal; Goess, Christian A; Mathieu, Suzanne L; Santora, Ling C.
Afiliação
  • Hobson AD; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Xu J; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Marvin CC; AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • McPherson MJ; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Hollmann M; AbbVie Deutschland GmbH & Co KG, Knollstrasse 50, 67061 Ludwigshafen, Germany.
  • Gattner M; AbbVie Deutschland GmbH & Co KG, Knollstrasse 50, 67061 Ludwigshafen, Germany.
  • Dzeyk K; AbbVie Deutschland GmbH & Co KG, Knollstrasse 50, 67061 Ludwigshafen, Germany.
  • Fettis MM; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Bischoff AK; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Wang L; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Fitzgibbons J; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Wang L; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Salomon P; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Hernandez A; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Jia Y; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Sarvaiya H; AbbVie Inc., 1000 Gateway Blvd., South San Francisco, California 94080, United States.
  • Goess CA; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Mathieu SL; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Santora LC; AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States.
J Med Chem ; 66(13): 9161-9173, 2023 07 13.
Article em En | MEDLINE | ID: mdl-37379257

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoconjugados Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoconjugados Idioma: En Ano de publicação: 2023 Tipo de documento: Article