Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression.

Zhou, Bingqian; Chen, Ningdai; Chen, Zheyi; Chen, Shiyu; Yang, Junyao; Zheng, Yingxia; Shen, Lisong

Zhou, Bingqian; Chen, Ningdai; Chen, Zheyi; Chen, Shiyu; Yang, Junyao; Zheng, Yingxia; Shen, Lisong.

Afiliação

Zhou B; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen N; Faculty of Medical Laboratory Science, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen Z; Institute of Artificial Intelligence Medicine, Shanghai Academy of Experimental Medicine, Shanghai, China.
Chen S; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yang J; Faculty of Medical Laboratory Science, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheng Y; Institute of Artificial Intelligence Medicine, Shanghai Academy of Experimental Medicine, Shanghai, China.
Shen L; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Eur J Immunol ; 53(10): e2250226, 2023 10.

Article em En | MEDLINE | ID: mdl-37389889

Assuntos

Neoplasias Colorretais; Proteína-Arginina N-Metiltransferases; Animais; Camundongos; Linhagem Celular Tumoral; Neoplasias Colorretais/genética; Isoformas de Proteínas/metabolismo; Proteína-Arginina N-Metiltransferases/genética; Proteína-Arginina N-Metiltransferases/metabolismo; Processamento Pós-Transcricional do RNA; RNA Mensageiro

Palavras-chave

B cells; Direct RNA sequencing; Poly(A); Prmt5; Splicing; m6A

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína-Arginina N-Metiltransferases / Neoplasias Colorretais Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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