Sleep disorders in Lewy body dementia: Mechanisms, clinical relevance, and unanswered questions.
Alzheimers Dement
; 19(11): 5264-5283, 2023 Nov.
Article
em En
| MEDLINE
| ID: mdl-37392199
ABSTRACT
In Lewy body dementia (LBD), disturbances of sleep and/or arousal including insomnia, excessive daytime sleepiness, rapid eye movement (REM) sleep behavior disorder, obstructive sleep apnea, and restless leg syndrome are common. These disorders can each exert a significant negative impact on both patient and caregiver quality of life; however, their etiology is poorly understood. Little guidance is available for assessing and managing sleep disorders in LBD, and they remain under-diagnosed and under-treated. This review aims to (1) describe the specific sleep disorders which occur in LBD, considering their putative or potential mechanisms; (2) describe the history and diagnostic process for these disorders in LBD; and (3) summarize current evidence for their management in LBD and consider some of the ongoing and unanswered questions in this field and future research directions.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transtornos do Sono-Vigília
/
Doença por Corpos de Lewy
/
Transtorno do Comportamento do Sono REM
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article