The Novel Role of Mitochondrial Citrate Synthase and Citrate in the Pathophysiology of Alzheimer's Disease.

Chhimpa, Neeraj; Singh, Neha; Puri, Nikkita; Kayath, Hanuman Prasad

Chhimpa, Neeraj; Singh, Neha; Puri, Nikkita; Kayath, Hanuman Prasad.

Afiliação

Chhimpa N; Department of Pharmacology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Singh N; Department of Pharmacology, Meharishi Markandeshwar College of Medical Science & Research, Ambala, India.
Puri N; Department of Pharmacology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Kayath HP; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.

J Alzheimers Dis ; 94(s1): S453-S472, 2023.

Article em En | MEDLINE | ID: mdl-37393492

Assuntos

Doença de Alzheimer; Humanos; Doença de Alzheimer/metabolismo; Ácido Cítrico; Citrato (si)-Sintase/metabolismo; Transportador de Glucose Tipo 3; Acetilcoenzima A/metabolismo; Citratos

Palavras-chave

APOEÉ4; Acetyl-CoA; Alzheimer's disease; GLUT3; acetylcholine; amyloid-beta; cellular bioenergetics; citrate; citrate synthase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article