CDK4-E2F3 signals enhance oxidative skeletal muscle fiber numbers and function to affect myogenesis and metabolism.

Bahn, Young Jae; Yadav, Hariom; Piaggi, Paolo; Abel, Brent S; Gavrilova, Oksana; Springer, Danielle A; Papazoglou, Ioannis; Zerfas, Patricia M; Skarulis, Monica C; McPherron, Alexandra C; Rane, Sushil G

Bahn, Young Jae; Yadav, Hariom; Piaggi, Paolo; Abel, Brent S; Gavrilova, Oksana; Springer, Danielle A; Papazoglou, Ioannis; Zerfas, Patricia M; Skarulis, Monica C; McPherron, Alexandra C; Rane, Sushil G.

Afiliação

Bahn YJ; Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Yadav H; Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Piaggi P; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, Arizona.
Abel BS; Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Gavrilova O; Mouse Metabolism Core Facility, National Institute of Diabetes and Digestive and Kidney Diseases.
Springer DA; Mouse Phenotyping Core, National Heart, Lung and Blood Institute.
Papazoglou I; Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Zerfas PM; Office of Research Services, and.
Skarulis MC; Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
McPherron AC; Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Rane SG; Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.

J Clin Invest ; 133(13)2023 07 03.

Article em En | MEDLINE | ID: mdl-37395281

Assuntos

Diabetes Mellitus Tipo 2; Doenças Musculares; Camundongos; Animais; Humanos; Diabetes Mellitus Tipo 2/genética; Diabetes Mellitus Tipo 2/metabolismo; Fibras Musculares Esqueléticas/metabolismo; Fibras Musculares de Contração Lenta/metabolismo; Músculo Esquelético/metabolismo; Doenças Musculares/metabolismo; Obesidade/metabolismo; Estresse Oxidativo; Desenvolvimento Muscular; Fator de Transcrição E2F3/metabolismo; Quinase 4 Dependente de Ciclina/genética; Quinase 4 Dependente de Ciclina/metabolismo

Palavras-chave

Metabolism; Mitochondria; Muscle Biology; Skeletal muscle

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Doenças Musculares Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Doenças Musculares Idioma: En Ano de publicação: 2023 Tipo de documento: Article