From cryogenic to on-scalp magnetoencephalography for the evaluation of paediatric epilepsy.
Dev Med Child Neurol
; 66(3): 298-306, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-37421175
ABSTRACT
Magnetoencephalography (MEG) is a neurophysiological technique based on the detection of brain magnetic fields. Whole-head MEG systems typically house a few hundred sensors requiring cryogenic cooling in a rigid one-size-fits-all (commonly adult-sized) helmet to keep a thermal insulation space. This leads to an increased brain-to-sensor distance in children, because of their smaller head circumference, and decreased signal-to-noise ratio. MEG allows detection and localization of interictal and ictal epileptiform discharges, and pathological high frequency oscillations, as a part of the presurgical assessment of children with refractory focal epilepsy, where electroencephalography is not contributive. MEG can also map the eloquent cortex before surgical resection. MEG also provides insights into the physiopathology of both generalized and focal epilepsy. On-scalp recordings based on cryogenic-free sensors have demonstrated their use in the field of childhood focal epilepsy and should become a reference technique for diagnosing epilepsy in the paediatric population. WHAT THIS PAPER ADDS Magnetoencephalography (MEG) contributes to the diagnosis and understanding of paediatric epilepsy. On-scalp MEG recordings demonstrate some advantages over cryogenic MEG.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Epilepsias Parciais
/
Epilepsia
/
Epilepsia Resistente a Medicamentos
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article