A Dutch highly pathogenic H5N6 avian influenza virus showed remarkable tropism for extra-respiratory organs and caused severe disease but was not transmissible via air in the ferret model.

Herfst, Sander; Begeman, Lineke; Spronken, Monique I; Poen, Marjolein J; Eggink, Dirk; de Meulder, Dennis; Lexmond, Pascal; Bestebroer, Theo M; Koopmans, Marion P G; Kuiken, Thijs; Richard, Mathilde; Fouchier, Ron A M

Herfst, Sander; Begeman, Lineke; Spronken, Monique I; Poen, Marjolein J; Eggink, Dirk; de Meulder, Dennis; Lexmond, Pascal; Bestebroer, Theo M; Koopmans, Marion P G; Kuiken, Thijs; Richard, Mathilde; Fouchier, Ron A M.

Afiliação

Herfst S; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Begeman L; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Spronken MI; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Poen MJ; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Eggink D; Academic Medical Center Amsterdam, Laboratory of Experimental Virology , Amsterdam, the Netherlands.
de Meulder D; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Lexmond P; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Bestebroer TM; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Koopmans MPG; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Kuiken T; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Richard M; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.
Fouchier RAM; Department of Viroscience, Erasmus University Medical Center , Rotterdam, the Netherlands.

mSphere ; 8(4): e0020023, 2023 08 24.

Article em En | MEDLINE | ID: mdl-37428085

Assuntos

Virus da Influenza A Subtipo H5N1; Vírus da Influenza A Subtipo H5N2; Vírus da Influenza A; Influenza Aviária; Humanos; Animais; Furões; Virus da Influenza A Subtipo H5N1/genética; Vírus da Influenza A Subtipo H5N2/genética; Vírus da Influenza A/genética; Aves Domésticas

Palavras-chave

H5N6; HPAI; ferret; influenza; pathogenesis; risk assessment; transmission

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Virus da Influenza A Subtipo H5N1 / Vírus da Influenza A Subtipo H5N2 / Influenza Aviária Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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