Nek6 knockdown polarized macrophages into a pro-inflammatory phenotype via inhibiting STAT3 expression.

Wu, Xiaoyan; Deng, Ke-Qiong; Cai, Huan-Huan; Zeng, Ziyue; Cao, Jian-Lei; Zhang, Lin; Lu, Zhibing; Cheng, Wen-Lin

Wu, Xiaoyan; Deng, Ke-Qiong; Cai, Huan-Huan; Zeng, Ziyue; Cao, Jian-Lei; Zhang, Lin; Lu, Zhibing; Cheng, Wen-Lin.

Afiliação

Wu X; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan, China.
Deng KQ; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan, China.
Cai HH; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan, China.
Zeng Z; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan, China.
Cao JL; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan, China.
Zhang L; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan, China.
Lu Z; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan, China.
Cheng WL; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan, China.

Int J Exp Pathol ; 104(5): 237-246, 2023 10.

Article em En | MEDLINE | ID: mdl-37431082

Assuntos

Macrófagos; Quinases Relacionadas a NIMA; Fator de Transcrição STAT3; Interleucina-4/farmacologia; Interleucina-4/metabolismo; Lipopolissacarídeos/farmacologia; Macrófagos/metabolismo; Fenótipo; RNA Interferente Pequeno; Animais; Camundongos; Quinases Relacionadas a NIMA/genética; Quinases Relacionadas a NIMA/metabolismo; Fator de Transcrição STAT3/metabolismo

Palavras-chave

Nek6; STAT3; macrophage polarization

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Transcrição STAT3 / Quinases Relacionadas a NIMA / Macrófagos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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