Assessing the performance of European-derived cardiometabolic polygenic risk scores in South-Asians and their interplay with family history.

Hassanin, Emadeldin; Maj, Carlo; Klinkhammer, Hannah; Krawitz, Peter; May, Patrick; Bobbili, Dheeraj Reddy

Hassanin, Emadeldin; Maj, Carlo; Klinkhammer, Hannah; Krawitz, Peter; May, Patrick; Bobbili, Dheeraj Reddy.

Afiliação

Hassanin E; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 6 avenue du Swing, Belvaux, L-4367, Luxembourg.
Maj C; Institute for Genomic Statistics and Bioinformatics, University of Bonn, Bonn, Germany.
Klinkhammer H; Centre for Human Genetics, University of Marburg, Marburg, Germany.
Krawitz P; Institute for Genomic Statistics and Bioinformatics, University of Bonn, Bonn, Germany.
May P; Medical Faculty, Institute for Medical Biometry, Informatics and Epidemiology, University Bonn, Bonn, Germany.
Bobbili DR; Institute for Genomic Statistics and Bioinformatics, University of Bonn, Bonn, Germany.

BMC Med Genomics ; 16(1): 164, 2023 07 12.

Article em En | MEDLINE | ID: mdl-37438803

Assuntos

Doença da Artéria Coronariana; Diabetes Mellitus Tipo 2; Obesidade Mórbida; Humanos; Doença da Artéria Coronariana/genética; Diabetes Mellitus Tipo 2/genética; Obesidade/genética; Fatores de Risco; Reino Unido; Povo Asiático; Herança Multifatorial

Palavras-chave

Coronary artery disease; Family History; Polygenic risk; South Asians; Type 2 diabetes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Obesidade Mórbida / Diabetes Mellitus Tipo 2 Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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