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Acaricidal activity of bioactive compounds isolated from Aspergillus oryzae against poultry red mites, Dermanyssus gallinae (Acari: Dermanyssidae).
Zhu, Kexin; Liu, Xin; Qi, Xiaoxiao; Liu, Qi; Wang, Bohan; Sun, Weiwei; Pan, Baoliang.
Afiliação
  • Zhu K; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
  • Liu X; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
  • Qi X; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
  • Liu Q; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
  • Wang B; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
  • Sun W; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. Electronic address: sunweiwei@cau.edu.cn.
  • Pan B; College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. Electronic address: baoliang@cau.edu.cn.
Vet Parasitol ; 320: 109983, 2023 Aug.
Article em En | MEDLINE | ID: mdl-37450962
Dermanyssus gallinae, the poultry red mite (PRM), is an obligate ectoparasite feeding on poultry blood, seriously affecting the health of layers and egg production. The control of PRMs mainly relies on chemical drugs, which is facing several challenges such as the environment pollution and drug resistance. Using fungal metabolites is an environmentally friendly alternative for the control of pests. However, few studies have been conducted on the efficacy of fungal metabolites against D. gallinae. In this study, five strains of fungi were isolated from D. gallinae under laboratory conditions, and their extracts with ethyl acetate were tested for acaricidal activity on D. gallinae. The crude extract of Aspergillus oryzae caused 75.55 ± 6.94% mortality of mites at a concentration of 12.5 mg/mL, showing the highest acaricidal effect in all extracts. Subsequently, the extract of A. oryzae was isolated by bio-guided fractionation, and ten major compounds were identified by LC-MS/MS analysis. The results of bioassays indicated that five compounds exhibited acaricidal activity against D. gallinae. N, N-dimethyldecylamine N-oxide was the optimal acaricidal compound with LC50 of 0.568 mg/mL. Additionally, palmitic acid, triethanolamine, cuminaldehyde, and 2,4-dimethylbenzaldehyde also showed acaricidal activity. These compounds have great application potential in the mite control, and the analysis of these fungal acaricidal substances provides a new idea and basis for the subsequent development of PRM control technology.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças das Aves Domésticas / Aspergillus oryzae / Trombiculidae / Acaricidas / Infestações por Ácaros / Ácaros Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças das Aves Domésticas / Aspergillus oryzae / Trombiculidae / Acaricidas / Infestações por Ácaros / Ácaros Idioma: En Ano de publicação: 2023 Tipo de documento: Article