Tumor necrosis factor-&#945;-induced protein 8-like 2 alleviates morphine antinociceptive tolerance through reduction of ROS-mediated apoptosis and MAPK/NF-&#954;B signaling pathways.

Yang, Zhong; Zhang, Feifei; Abdul, Mannan; Jiang, Jinhong; Li, Yanqiang; Li, Yeqi; Yin, Cui; Xing, Yanhong; Liu, Su; Lu, Chen

Tumor necrosis factor-α-induced protein 8-like 2 alleviates morphine antinociceptive tolerance through reduction of ROS-mediated apoptosis and MAPK/NF-κB signaling pathways.

Yang, Zhong; Zhang, Feifei; Abdul, Mannan; Jiang, Jinhong; Li, Yanqiang; Li, Yeqi; Yin, Cui; Xing, Yanhong; Liu, Su; Lu, Chen.

Afiliação

Yang Z; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Zhang F; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Abdul M; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China; Department of Anesthesiology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Jiang J; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Li Y; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Li Y; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Yin C; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Xing Y; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Liu S; Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China. Electronic address: 150040009@qq.com.
Lu C; School of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China. Electronic address: lucoct@163.com.

Neuropharmacology ; 238: 109667, 2023 11 01.

Article em En | MEDLINE | ID: mdl-37451333

Assuntos

Morfina; Neuroblastoma; Humanos; Camundongos; Animais; Morfina/farmacologia; Morfina/metabolismo; NF-kappa B/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Neuroblastoma/patologia; Corno Dorsal da Medula Espinal/metabolismo; Medula Espinal/metabolismo; Transdução de Sinais; Analgésicos/farmacologia; Analgésicos/metabolismo; Apoptose; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo

Palavras-chave

Apoptosis; MAPK; Morphine tolerance; NF-κB; ROS; TIPE2

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morfina / Neuroblastoma Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morfina / Neuroblastoma Idioma: En Ano de publicação: 2023 Tipo de documento: Article