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Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity.
Rodriguez, Martin; Trevisan, Brady; Ramamurthy, Ritu M; George, Sunil K; Diaz, Jonathan; Alexander, Jordan; Meares, Diane; Schwahn, Denise J; Quilici, David R; Figueroa, Jorge; Gautreaux, Michael; Farland, Andrew; Atala, Anthony; Doering, Christopher B; Spencer, H Trent; Porada, Christopher D; Almeida-Porada, Graça.
Afiliação
  • Rodriguez M; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine (WFSOM), Winston Salem, NC, USA.
  • Trevisan B; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine (WFSOM), Winston Salem, NC, USA.
  • Ramamurthy RM; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine (WFSOM), Winston Salem, NC, USA.
  • George SK; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine (WFSOM), Winston Salem, NC, USA.
  • Diaz J; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine (WFSOM), Winston Salem, NC, USA.
  • Alexander J; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, GA, USA.
  • Meares D; Special Hematology Laboratory, Wake Forest School of Medicine, Winston Salem, NC, USA.
  • Schwahn DJ; Preclinical Development, Wave Life Sciences, Lexington, MA, USA.
  • Quilici DR; The Mick Hitchcock Ph.D. Nevada Proteomics Center, University of Nevada Reno, Reno, NV, USA.
  • Figueroa J; Center for Research in Obstetrics and Gynecology, WFSOM, Winston Salem, NC, USA.
  • Gautreaux M; HLA/Immunogenetics and Immunodiagnostics Laboratories, Winston Salem, NC, USA.
  • Farland A; Special Hematology Laboratory, Wake Forest School of Medicine, Winston Salem, NC, USA.
  • Atala A; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine (WFSOM), Winston Salem, NC, USA.
  • Doering CB; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, GA, USA.
  • Spencer HT; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, GA, USA.
  • Porada CD; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine (WFSOM), Winston Salem, NC, USA.
  • Almeida-Porada G; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine (WFSOM), Winston Salem, NC, USA. galmeida@wakehealth.edu.
Nat Commun ; 14(1): 4206, 2023 07 14.
Article em En | MEDLINE | ID: mdl-37452013
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemofilia A Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemofilia A Idioma: En Ano de publicação: 2023 Tipo de documento: Article