NFAT signaling dysregulation in cancer: Emerging roles in cancer stem cells.
Biomed Pharmacother
; 165: 115167, 2023 Sep.
Article
em En
| MEDLINE
| ID: mdl-37454598
ABSTRACT
The nuclear factor of activated T cells (NFAT) was first identified as a transcriptional regulator of activated T cells. The NFAT family is involved in the development of tumors. Furthermore, recent evidence reveals that NFAT proteins regulate the development of inflammatory and immune responses. New discoveries have also been made about the mechanisms by which NFAT regulates cancer progression through cancer stem cells (CSC). Here, we discuss the role of the NFAT family in the immune system and various cancer types.
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Base de dados:
MEDLINE
Assunto principal:
Fatores de Transcrição NFATC
/
Neoplasias
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article