CA9 knockdown enhanced ionizing radiation-induced ferroptosis and radiosensitivity of hypoxic glioma cells.

Huang, Wenpeng; He, Yuping; Yang, Shuangyu; Xue, Xuefei; Qin, Hualong; Sun, Ting; Yang, Wei

Huang, Wenpeng; He, Yuping; Yang, Shuangyu; Xue, Xuefei; Qin, Hualong; Sun, Ting; Yang, Wei.

Afiliação

Huang W; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, Jiangsu, China.
He Y; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, Jiangsu, China.
Yang S; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, Jiangsu, China.
Xue X; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, Jiangsu, China.
Qin H; Department of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Sun T; Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Yang W; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, Jiangsu, China.

Int J Radiat Biol ; 99(12): 1908-1924, 2023.

Article em En | MEDLINE | ID: mdl-37463506

Assuntos

Anidrase Carbônica IX; Ferroptose; Glioma; Tolerância a Radiação; Hipóxia Tumoral; Glioma/genética; Glioma/radioterapia; Radiação Ionizante; Anidrase Carbônica IX/genética; Técnicas de Silenciamento de Genes; Linhagem Celular Tumoral; Humanos; Animais; Camundongos; Alarminas/metabolismo; Peroxidação de Lipídeos

Palavras-chave

DAMPs; Glioma; ferroptosis; hypoxia; radiosensitivity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tolerância a Radiação / Anidrase Carbônica IX / Ferroptose / Glioma Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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