A novel fluorescent probe based on naphthimide for H2S identification and application.
Anal Biochem
; 677: 115232, 2023 09 15.
Article
em En
| MEDLINE
| ID: mdl-37481195
ABSTRACT
In view of the superior chemical activity of selenoether bond (-Se-) and the excellent optical properties of naphthimide, a novel fluorescent probe (NapSe) with near-rectangular structure, which contains double naphthimide fluorophores linked by selenoether bond, is designed for specific fluorescence detection of hydrogen sulfide (H2S). NapSe has excellent optical properties super large Stokes Shift (190 nm) and good stability in a wide pH range. The selectivity of NapSe fluorescence detection of H2S is high, and displays excellent "turn-on" phenomenon and strong anti-interference. And the fluorescence intensity increased obviously, reaching 42 times. The time response of probe NapSe is very rapid (3 min) compared with other fluorescence probes that respond to H2S. It shows high sensitivity by calculating the detection limit (LOD) as low as 5.4 µM. Notably, the identification of H2S by probe NapSe has been successfully applied to the detection of test paper and the detection of exogenous and endogenous fluorescence imaging of MCF-7 breast cancer cells.
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Base de dados:
MEDLINE
Assunto principal:
Corantes Fluorescentes
/
Sulfeto de Hidrogênio
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article