Circulating macrophages as the mechanistic link between mosaic loss of Y-chromosome and cardiac disease.

Xu, Xuehong; Zhou, Rong; Duan, Qinchun; Miao, Yuanlin; Zhang, Tingting; Wang, Mofei; Jones, Odell D; Xu, MengMeng

Xu, Xuehong; Zhou, Rong; Duan, Qinchun; Miao, Yuanlin; Zhang, Tingting; Wang, Mofei; Jones, Odell D; Xu, MengMeng.

Afiliação

Xu X; Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences and University Hospital Medical Center, 620 West Chang'an, Chang'an District, Xi'an, 710119, China. xhx0708@snnu.edu.cn.
Zhou R; Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences and University Hospital Medical Center, 620 West Chang'an, Chang'an District, Xi'an, 710119, China.
Duan Q; Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences and University Hospital Medical Center, 620 West Chang'an, Chang'an District, Xi'an, 710119, China.
Miao Y; Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences and University Hospital Medical Center, 620 West Chang'an, Chang'an District, Xi'an, 710119, China.
Zhang T; Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences and University Hospital Medical Center, 620 West Chang'an, Chang'an District, Xi'an, 710119, China.
Wang M; Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences and University Hospital Medical Center, 620 West Chang'an, Chang'an District, Xi'an, 710119, China.
Jones OD; University of Pennsylvania School of Medicine ULAR, Philadelphia, PA, 19144, USA.
Xu M; Department of Pediatrics, Morgan Stanley Children's Hospital, Columbia University, 3959 Broadway, New York, NY, 10032, USA. mex9002@nyp.org.

Cell Biosci ; 13(1): 135, 2023 Jul 24.

Article em En | MEDLINE | ID: mdl-37488646

Palavras-chave

Age-related cardiac disease; Cardiac fibrosis; Hematopoietic macrophage; Mosaic loss of Y-chromosome (mLOY); Profibrotic regulons; Proliferation of cardiac fibroblast

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article