The interplay between lipid droplets and virus infection.
J Med Virol
; 95(7): e28967, 2023 07.
Article
em En
| MEDLINE
| ID: mdl-37496184
ABSTRACT
As an intracellular parasite, the virus usurps cellular machinery and modulates cellular metabolism pathways to replicate itself in cells. Lipid droplets (LDs) are universally conserved energy storage organelles that not only play vital roles in maintaining lipid homeostasis but are also involved in viral replication. Increasing evidence has demonstrated that viruses take advantage of cellular lipid metabolism by targeting the biogenesis, hydrolysis, and lipophagy of LD during viral infection. In this review, we summarize the current knowledge about the modulation of cellular LD by different viruses, with a special emphasis on the Hepatitis C virus, Dengue virus, and SARS-CoV-2.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Gotículas Lipídicas
/
COVID-19
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article