Synthesis, characterization, and biological activity of some 2,4-diketo esters containing dehydrozingerone fragment: DNA and protein binding study.

Mihajlovic, Kristina; Joksimovic, Nenad; Jankovic, Nenad; Milovic, Emilija; Petronijevic, Jelena; Filipovic, Ignjat; Muskinja, Jovana; Petrovic, Nevena; Kosanic, Marijana

Mihajlovic, Kristina; Joksimovic, Nenad; Jankovic, Nenad; Milovic, Emilija; Petronijevic, Jelena; Filipovic, Ignjat; Muskinja, Jovana; Petrovic, Nevena; Kosanic, Marijana.

Afiliação

Mihajlovic K; University of Kragujevac, Faculty of Science, Department of Chemistry, Radoja Domanovica 12, 34000 Kragujevac, Serbia.
Joksimovic N; University of Kragujevac, Faculty of Science, Department of Chemistry, Radoja Domanovica 12, 34000 Kragujevac, Serbia. Electronic address: nenad.joksimovic@pmf.kg.ac.rs.
Jankovic N; University of Kragujevac, Institute for Information Technologies Kragujevac, Department of Sciences, Jovana Cvijica bb, 34000 Kragujevac, Serbia.
Milovic E; University of Kragujevac, Institute for Information Technologies Kragujevac, Department of Sciences, Jovana Cvijica bb, 34000 Kragujevac, Serbia.
Petronijevic J; University of Kragujevac, Faculty of Science, Department of Chemistry, Radoja Domanovica 12, 34000 Kragujevac, Serbia.
Filipovic I; University of Kragujevac, Faculty of Science, Department of Chemistry, Radoja Domanovica 12, 34000 Kragujevac, Serbia.
Muskinja J; University of Kragujevac, Institute for Information Technologies Kragujevac, Department of Sciences, Jovana Cvijica bb, 34000 Kragujevac, Serbia.
Petrovic N; University of Kragujevac, Faculty of Science, Department of Biology and Ecology, Radoja Domanovica 12, 34000 Kragujevac, Serbia.
Kosanic M; University of Kragujevac, Faculty of Science, Department of Biology and Ecology, Radoja Domanovica 12, 34000 Kragujevac, Serbia.

Bioorg Med Chem Lett ; 93: 129413, 2023 09 01.

Article em En | MEDLINE | ID: mdl-37499986

Assuntos

Anti-Infecciosos; Ésteres; Ligação Proteica; Simulação de Acoplamento Molecular; Ésteres/farmacologia; Soroalbumina Bovina/química; Antibacterianos/química; DNA/química; Testes de Sensibilidade Microbiana; Bactérias Gram-Positivas

Palavras-chave

2,4-Diketo esters; Antimicrobial activity; Biological activity; DNA interactions; Molecular docking; Protein binding study; Synthesis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ésteres / Anti-Infecciosos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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XML

PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ésteres / Anti-Infecciosos Idioma: En Ano de publicação: 2023 Tipo de documento: Article