The immunoproteasome subunit ß2i ameliorates myocardial ischemia/reperfusion injury by regulating Parkin-Mfn1/2-mediated mitochondrial fusion.

Su, Hui-Xiang; Li, Pang-Bo; Shi, Kai-Na; Gao, Jing; Zhang, Hong-Jia; Li, Hui-Hua

Su, Hui-Xiang; Li, Pang-Bo; Shi, Kai-Na; Gao, Jing; Zhang, Hong-Jia; Li, Hui-Hua.

Afiliação

Su HX; Department of Emergency Medicine, Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Worker's Stadium South Road, Beijing, 100020, China.
Li PB; Department of Emergency Medicine, Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Worker's Stadium South Road, Beijing, 100020, China.
Shi KN; Department of Emergency Medicine, Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Worker's Stadium South Road, Beijing, 100020, China.
Gao J; Department of Emergency Medicine, Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Worker's Stadium South Road, Beijing, 100020, China.
Zhang HJ; Department of Cardiac Surgery, Beijing An-Zhen Hospital, Capital Medical University, No. 2 An-Zhen Road, Chaoyang District, Beijing, 100029, China. zhanghongjia722@ccmu.edu.cn.
Li HH; Department of Emergency Medicine, Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Worker's Stadium South Road, Beijing, 100020, China. hhli1935@aliyun.com.

Cell Mol Life Sci ; 80(8): 231, 2023 Jul 27.

Article em En | MEDLINE | ID: mdl-37501008

Assuntos

Traumatismo por Reperfusão Miocárdica; Camundongos; Animais; Traumatismo por Reperfusão Miocárdica/genética; Traumatismo por Reperfusão Miocárdica/metabolismo; Dinâmica Mitocondrial/fisiologia; Coração; Ubiquitina-Proteína Ligases/genética; Ubiquitina-Proteína Ligases/metabolismo; Apoptose; Camundongos Knockout; Hidrolases/metabolismo; Miócitos Cardíacos/metabolismo; GTP Fosfo-Hidrolases/genética; GTP Fosfo-Hidrolases/metabolismo

Palavras-chave

Cardiac ischemia/reperfusion; Catalytic subunit ß2i; Immunoproteasome; Mfn1/2; Mitochondrial dynamics; Parkin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão Miocárdica Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão Miocárdica Idioma: En Ano de publicação: 2023 Tipo de documento: Article