3-hydroxykynurenine is a ROS-inducing cytotoxic tryptophan metabolite that disrupts the TCA cycle.

Buchanan, Jane L; Rauckhorst, Adam J; Taylor, Eric B.

Afiliação

Buchanan JL; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA 52240, USA.
Rauckhorst AJ; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA 52240, USA.
Taylor EB; FOEDRC Metabolomics Core Research Facility, University of Iowa Carver College of Medicine, Iowa City, IA 52240, USA.

bioRxiv ; 2023 Jul 10.

Article em En | MEDLINE | ID: mdl-37502990