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Inflammation induced by tumor-associated nerves promotes resistance to anti-PD-1 therapy in cancer patients and is targetable by interleukin-6 blockade.
Baruch, Erez N; Nagarajan, Priyadahrshini; Gleber-Netto, Frederico O; Rao, Xiayu; Xie, Tongxin; Akhter, Shamima; Adewale, Adebayo; Shajedul, Islam; Mattson, Brandi J; Ferrarotto, Renata; Wong, Michael K; Davies, Michael A; Jindal, Sonali; Basu, Sreyashi; Harwood, Catherine; Leigh, Irene; Ajami, Nadim; Futreal, Andrew; Castillo, Micah; Gunaratne, Preethi; Goepfert, Ryan P; Khushalani, Nikhil; Wang, Jing; Watowich, Stephanie; Calin, George A; Migden, Michael R; Vermeer, Paola; D'Silva, Nisha; Yaniv, Dan; Burks, Jared K; Gomez, Javier; Dougherty, Patrick M; Tsai, Kenneth Y; Allison, James P; Sharma, Padmanee; Wargo, Jennifer; Myers, Jeffrey N; Gross, Neil D; Amit, Moran.
Afiliação
  • Baruch EN; Division of Cancer Medicine, Hematology and Oncology Fellowship program, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Nagarajan P; Department of Pathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gleber-Netto FO; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Rao X; Department of Bioinformatics and Computational Biology, Division of Basic Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Xie T; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Akhter S; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Adewale A; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Shajedul I; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Mattson BJ; The Neurodegeneration Consortium, Therapeutics Discovery Division, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ferrarotto R; Department of Head and Neck Thoracic Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wong MK; Department of Melanoma Medical Oncology, Division of Cancer Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Davies MA; Department of Melanoma Medical Oncology, Division of Cancer Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Jindal S; Department of Immunology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Basu S; Department of Immunology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Harwood C; Department of Dermatology, Royal London Hospital, Barts Health NHS Trust, Centre for Cell Biology and Cutaneous Research, Blizard Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London, UK.
  • Leigh I; Department of Dermatology, Royal London Hospital, Barts Health NHS Trust, Centre for Cell Biology and Cutaneous Research, Blizard Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London, UK.
  • Ajami N; Department of Genomic Medicine, Division of Cancer Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Futreal A; Department of Genomic Medicine, Division of Cancer Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Castillo M; Department of Biology and Biochemistry, University of Houston Sequencing and Gene Editing Core, University of Houston, Houston, TX, USA.
  • Gunaratne P; Department of Biology and Biochemistry, University of Houston Sequencing and Gene Editing Core, University of Houston, Houston, TX, USA.
  • Goepfert RP; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Khushalani N; Department of Tumor Biology, Moffitt Cancer Center, Tampa, FL, USA.
  • Wang J; Department of Bioinformatics and Computational Biology, Division of Basic Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Watowich S; Department of Immunology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Calin GA; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Migden MR; Department of Dermatology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Vermeer P; Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, USA.
  • D'Silva N; Department of Dentistry & Pathology, the University of Michigan, Ann Arbor, MI, USA.
  • Yaniv D; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Burks JK; Department of Leukemia, Division of Cancer Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gomez J; Department of Leukemia, Division of Cancer Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Dougherty PM; Department of Pain Medicine, Division of Anesthesiology, Critical Care, and Pain Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Tsai KY; Department of Tumor Biology, Moffitt Cancer Center, Tampa, FL, USA.
  • Allison JP; Department of Immunology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Sharma P; Department of Immunology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wargo J; Department of Genomic Medicine, Division of Cancer Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Myers JN; Department of Surgical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gross ND; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Amit M; Department of Head and Neck Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Res Sq ; 2023 Jul 18.
Article em En | MEDLINE | ID: mdl-37503252
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article