Targeting SOX18 Transcription Factor Activity by Small-Molecule Inhibitor Sm4 in Non-Small Lung Cancer Cell Lines.

Rodak, Olga; Mrozowska, Monika; Rusak, Agnieszka; Gomulkiewicz, Agnieszka; Piotrowska, Aleksandra; Olbromski, Mateusz; Podhorska-Okolów, Marzenna; Ugorski, Maciej; Dziegiel, Piotr

Rodak, Olga; Mrozowska, Monika; Rusak, Agnieszka; Gomulkiewicz, Agnieszka; Piotrowska, Aleksandra; Olbromski, Mateusz; Podhorska-Okolów, Marzenna; Ugorski, Maciej; Dziegiel, Piotr.

Afiliação

Rodak O; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Mrozowska M; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Rusak A; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Gomulkiewicz A; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Piotrowska A; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Olbromski M; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Podhorska-Okolów M; Division of Ultrastructural Research, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Ugorski M; Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Dziegiel P; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.

Int J Mol Sci ; 24(14)2023 Jul 11.

Article em En | MEDLINE | ID: mdl-37511076

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Humanos; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/patologia; Fatores de Transcrição SOXF/genética; Fatores de Transcrição SOXF/metabolismo; Regulação Neoplásica da Expressão Gênica; Linhagem Celular; Linhagem Celular Tumoral

Palavras-chave

SOX18; adenocarcinoma; cell cycle arrest; non-small lung cancer; p21; small-molecule inhibitor; squamous carcinoma; transcription factors

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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