Low Glucose plus ß-Hydroxybutyrate Induces an Enhanced Inflammatory Response in Yak Alveolar Macrophages via Activating the GPR109A/NF-&#954;B Signaling Pathway.

Qi, Jiancheng; Yang, Qiyuan; Xia, Qing; Huang, Fangyuan; Guo, Hongrui; Cui, Hengmin; Xie, Yue; Ren, Zhihua; Gou, Liping; Cai, Dongjie; Kumbhar, Maqsood Ahmed; Fang, Jing; Zuo, Zhicai

Low Glucose plus ß-Hydroxybutyrate Induces an Enhanced Inflammatory Response in Yak Alveolar Macrophages via Activating the GPR109A/NF-κB Signaling Pathway.

Qi, Jiancheng; Yang, Qiyuan; Xia, Qing; Huang, Fangyuan; Guo, Hongrui; Cui, Hengmin; Xie, Yue; Ren, Zhihua; Gou, Liping; Cai, Dongjie; Kumbhar, Maqsood Ahmed; Fang, Jing; Zuo, Zhicai.

Afiliação

Qi J; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Yang Q; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Xia Q; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Huang F; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Guo H; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Cui H; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Xie Y; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Ren Z; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Gou L; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Cai D; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Kumbhar MA; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Fang J; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Zuo Z; Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.

Int J Mol Sci ; 24(14)2023 Jul 11.

Article em En | MEDLINE | ID: mdl-37511091

Assuntos

Macrófagos Alveolares; NF-kappa B; Bovinos; Animais; NF-kappa B/metabolismo; Ácido 3-Hidroxibutírico/farmacologia; Macrófagos Alveolares/metabolismo; Interleucina-6/farmacologia; Transdução de Sinais; Citocinas/metabolismo; Fator de Necrose Tumoral alfa/farmacologia; Glucose/farmacologia

Palavras-chave

low glucose; primary alveolar macrophages (AMs); pro-inflammatory response; yak; ß-hydroxybutyrate (BHB)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Macrófagos Alveolares Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Macrófagos Alveolares Idioma: En Ano de publicação: 2023 Tipo de documento: Article