Oral administration of Limonin (LM) exerts neuroprotective effects by inhibiting neuron autophagy and microglial activation in 6-OHDA-injected rats.

Gao, Xiyu; He, Dewei; Liu, Yanting; Cui, Mingchi; Li, Zhe; Li, Jie; He, Yuan; Wang, Hefei; Ye, Bojian; Fu, Shoupeng; Liu, Dianfeng

Gao, Xiyu; He, Dewei; Liu, Yanting; Cui, Mingchi; Li, Zhe; Li, Jie; He, Yuan; Wang, Hefei; Ye, Bojian; Fu, Shoupeng; Liu, Dianfeng.

Afiliação

Gao X; College of Animal Science, Jilin University, Changchun, China. Electronic address: xiyug21@mails.jlu.edu.cn.
He D; College of Animal Science, Jilin University, Changchun, China. Electronic address: m13144303829@163.com.
Liu Y; Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea. Electronic address: yantingliu02@gmail.com.
Cui M; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: 17649607145@163.com.
Li Z; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: lizhe9920@mails.jlu.edu.cn.
Li J; College of Animal Science, Jilin University, Changchun, China. Electronic address: lijie9920@mails.jlu.edu.cn.
He Y; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: heyuan9919@mails.jlu.edu.cn.
Wang H; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: Wanghf9919@mails.jlu.edu.cn.
Ye B; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: yebj871781602@163.com.
Fu S; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: fushoupeng@jlu.edu.cn.
Liu D; College of Animal Science, Jilin University, Changchun, China. Electronic address: ccldf@163.com.

Int Immunopharmacol ; 123: 110739, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37536186

Assuntos

Limoninas; Fármacos Neuroprotetores; Doença de Parkinson; Humanos; Ratos; Animais; Idoso; Pessoa de Meia-Idade; Oxidopamina/efeitos adversos; Oxidopamina/metabolismo; Microglia; Fármacos Neuroprotetores/farmacologia; Fármacos Neuroprotetores/uso terapêutico; Fármacos Neuroprotetores/metabolismo; Limoninas/farmacologia; Doença de Parkinson/metabolismo; Neurônios; Inflamação/tratamento farmacológico; Administração Oral; Autofagia

Palavras-chave

Apoptosis; Autophagy; Limonin; Neuroinflammation; Parkinson's disease

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Fármacos Neuroprotetores / Limoninas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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