pH-triggered "PEG" sheddable and folic acid-targeted nanoparticles for docetaxel delivery in breast cancer treatment.

Sui, Fangqian; Fang, Zengjun; Li, Lingjun; Wan, Xinhuan; Zhang, Yongqing; Cai, Xiaoqing

Sui, Fangqian; Fang, Zengjun; Li, Lingjun; Wan, Xinhuan; Zhang, Yongqing; Cai, Xiaoqing.

Afiliação

Sui F; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China.
Fang Z; Department of Pharmacy, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Li L; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China.
Wan X; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China.
Zhang Y; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China.
Cai X; School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China. Electronic address: caixiaoqing0901@163.com.

Int J Pharm ; 644: 123293, 2023 Sep 25.

Article em En | MEDLINE | ID: mdl-37541534

Assuntos

Antineoplásicos; Neoplasias da Mama; Nanopartículas; Humanos; Feminino; Docetaxel/farmacologia; Neoplasias da Mama/tratamento farmacológico; Ácido Fólico; Antineoplásicos/farmacologia; Polietilenoglicóis/uso terapêutico; Concentração de Íons de Hidrogênio; Linhagem Celular Tumoral; Portadores de Fármacos/uso terapêutico

Palavras-chave

Breast cancer; Charge-shielded; FA-targeted nanoparticles; Step-by-step pH-responsive; "PEG" sheddable

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Nanopartículas / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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